Relationship between gut microbiota and circulating metabolites in population-based cohorts.
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ABSTRACT:
SUBMITTER: Vojinovic D
PROVIDER: S-EPMC6925111 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Relationship between gut microbiota and circulating metabolites in population-based cohorts.
Vojinovic Dina D Radjabzadeh Djawad D Kurilshikov Alexander A Amin Najaf N Wijmenga Cisca C Franke Lude L Ikram M Arfan MA Uitterlinden Andre G AG Zhernakova Alexandra A Fu Jingyuan J Kraaij Robert R van Duijn Cornelia M CM
Nature communications 20191220 1
Gut microbiota has been implicated in major diseases affecting the human population and has also been linked to triglycerides and high-density lipoprotein levels in the circulation. Recent development in metabolomics allows classifying the lipoprotein particles into more details. Here, we examine the impact of gut microbiota on circulating metabolites measured by Nuclear Magnetic Resonance technology in 2309 individuals from the Rotterdam Study and the LifeLines-DEEP cohort. We assess the relati ...[more]
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