Ontology highlight
ABSTRACT:
SUBMITTER: Taib B
PROVIDER: S-EPMC6925201 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Taïb Bouchra B Aboussalah Amine M AM Moniruzzaman Mohammed M Chen Suming S Haughey Norman J NJ Kim Sangwon F SF Ahima Rexford S RS
Scientific reports 20191220 1
Glioblastoma multiforme (GBM) is the most common and lethal primary malignant brain tumor in adults. Despite the multimodal standard treatments for GBM, the median survival is still about one year. Analysis of brain tissues from GBM patients shows that lipid droplets are highly enriched in tumor tissues while undetectable in normal brain tissues, yet the identity and functions of lipid species in GBM are not well understood. The aims of the present work are to determine how GBM utilizes fatty ac ...[more]