Ontology highlight
ABSTRACT:
SUBMITTER: Tomar V
PROVIDER: S-EPMC6925231 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Tomar Vartika V Kumar Neeraj N Kumar Neeraj N Tomar Ravi R Sood Damini D Dhiman Neerupma N Dass Sujata K SK Prakash Satya S Madan Jitender J Chandra Ramesh R
Scientific reports 20191220 1
In present investigation, an attempt was undertaken to modify the C-9 position of noscapine (Nos), an opium alkaloid to yield 9 -hydroxy methyl and 9 -carbaldehyde oxime analogues for augmenting anticancer potential. The synthesis of 9-hydroxy methyl analogue of Nos was carried out by Blanc reaction and 9-carbaldehyde oxime was engineered by oxime formation method and characterized using FT-IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, mass spectroscopy, and so on techniques. In silico docking tech ...[more]