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A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).


ABSTRACT: Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades. The primary purpose of this Perspectives article was to provide a new research framework for advancing Latino ADRD knowledge, encompassing the unique sociocultural, cardiometabolic, and genomic aspects of Latino health, aging, and ADRD. In addition, we describe some of the research challenges to progress in Latino ADRD research. Finally, we present the Study of Latinos - Investigation of Neurocognitive Aging (SOL-INCA) as an example of implementing this new framework for advancing Latino ADRD research.

SUBMITTER: Gonzalez HM 

PROVIDER: S-EPMC6925624 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

González Hector M HM   Tarraf Wassim W   Fornage Myriam M   González Kevin A KA   Chai Albert A   Youngblood Marston M   Abreu Maria de Los Angeles MLA   Zeng Donglin D   Thomas Sonia S   Talavera Gregory A GA   Gallo Linda C LC   Kaplan Robert R   Daviglus Martha L ML   Schneiderman Neil N  

Alzheimer's & dementia : the journal of the Alzheimer's Association 20191120 12


Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades. The primary purpose of this Perspectives article was to provide a new research framework for advancing Latino ADRD knowledg  ...[more]

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