Ontology highlight
ABSTRACT:
SUBMITTER: Dineen RA
PROVIDER: S-EPMC6926372 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
NeuroImage. Clinical 20191126
<h4>Background</h4>Ataxia Telangiectasia (A-T) is an inherited multisystem disorder with cerebellar neurodegeneration. The relationships between imaging metrics of cerebellar health and neurological function across childhood in A-T are unknown, but may be important for determining timing and impact of therapeutic interventions.<h4>Purpose</h4>To test the hypothesis that abnormalities of cerebellar structure, physiology and cellular health occur in childhood A-T and correlate with neurological di ...[more]