Ontology highlight
ABSTRACT:
SUBMITTER: Caval-Holme F
PROVIDER: S-EPMC6927338 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Current biology : CB 20191107 23
Detection of ambient illumination in the developing retina prior to maturation of conventional photoreceptors is mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs) and is critical for driving several physiological processes, including light aversion, pupillary light reflexes, and photoentrainment of circadian rhythms. The strategies by which ipRGCs encode variations in ambient light intensity at these early ages are not known. Using unsupervised clustering of two-photon cal ...[more]