Ontology highlight
ABSTRACT:
SUBMITTER: Jennbacken K
PROVIDER: S-EPMC6928864 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Jennbacken Karin K Wågberg Fredrik F Karlsson Ulla U Eriksson Jerry J Magnusson Lisa L Chimienti Marjorie M Ricchiuto Piero P Bernström Jenny J Ding Mei M Ross-Thriepland Douglas D Xue Yafeng Y Peiris Diluka D Aastrup Teodor T Tegel Hanna H Hober Sophia S Sivertsson Åsa Å Uhlén Mathias M Strömstedt Per-Erik PE Davies Rick R Holmberg Schiavone Lovisa L
International journal of molecular sciences 20191130 23
Paracrine factors can induce cardiac regeneration and repair post myocardial infarction by stimulating proliferation of cardiac cells and inducing the anti-fibrotic, antiapoptotic, and immunomodulatory effects of angiogenesis. Here, we screened a human secretome library, consisting of 923 growth factors, cytokines, and proteins with unknown function, in a phenotypic screen with human cardiac progenitor cells. The primary readout in the screen was proliferation measured by nuclear count. From thi ...[more]