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The Role of Immune Cells and Cytokines in Intestinal Wound Healing.


ABSTRACT: Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells) and four cytokines (interleukin-10, tumor necrosis factor alpha, interleukin-6, and interleukin-22) to the wound repair process in the gut. Better understanding of these immune factors will be important for developing novel targeted therapy.

SUBMITTER: Xue X 

PROVIDER: S-EPMC6929186 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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The Role of Immune Cells and Cytokines in Intestinal Wound Healing.

Xue Xiang X   Falcon Daniel M DM  

International journal of molecular sciences 20191203 23


Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells) and four cytokines (interleukin-10, tumor necrosis factor alpha, interleukin-6, and interleukin-22) to the wound repair process in the gut. Better understanding of these immune factors will be import  ...[more]

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