Ontology highlight
ABSTRACT:
SUBMITTER: Haikal C
PROVIDER: S-EPMC6929290 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Translational neurodegeneration 20191224
Parkinson's disease is characterized by dopaminergic neuron loss and intracellular inclusions composed mainly of alpha synuclein (α-syn), but the mechanism of pathogenesis is still obscure. In recent years, more attention has been given to the gut as a key player in the initiation and progression of PD pathology. Several studies characterizing changes in the microbiome, particularly the gut microbiome, have been conducted. Although many studies found a decrease in the bacterial family Prevotella ...[more]