Dataset Information

Toxoplasma gondii And Neospora caninum In Brain Tissue Of Rodents In North-West Iran.

ABSTRACT: Purpose:Rodents live in proximity to humans and domestic animals. These creatures can serve as reservoir hosts for many zoonotic parasites; therefore, they increase the risk of human infections. The aim of this study was to investigate Toxoplasma gondii and Neospora caninum in rodents caught in Meshgin-Shahr District, Iran. Patients and methods:In a cross-sectional study, brain samples were collected from 70 rodents caught in Meshgin-Shahr District during March and December 2015. The specimens were examined for exposure to T. gondii and N. caninum with molecular methods. Results:Seventy rodents were caught, including 50 Meriones persicus, 11 Mus musculus and 9 Cricetulus migratorius. Thirty rodents were female and 40 were males. Using PCR (B1 gene), T. gondii was detected in 7.1% (5/70) of the rodents while N. caninum was not detected. The prevalence of Toxoplasma infection was higher in female rodents (4.28%) compared to male rodents (2.86%), but the difference was not significant. Conclusion:The results showed a low risk of T. gondii and N. caninum among rodents. Finally, further research is needed to understand the role of these rodent species in the transmission of the above protozoan pathogens to humans and livestock in this area.

SUBMITTER: Nazari N

PROVIDER: S-EPMC6929938 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

<i>Toxoplasma gondii</i> And <i>Neospora caninum</i> In Brain Tissue Of Rodents In North-West Iran.

Nazari Naser N Shojaee Saeedeh S Mohebali Mehdi M Teimouri Aref A Ghadiri Keyghobad K Raeghi Saber S Shiee Mohammad Reza MR Azarakhsh Yousef Y Bozorgomid Arezoo A

Veterinary medicine (Auckland, N.Z.) 20191220

<h4>Purpose</h4>Rodents live in proximity to humans and domestic animals. These creatures can serve as reservoir hosts for many zoonotic parasites; therefore, they increase the risk of human infections. The aim of this study was to investigate <i>Toxoplasma gondii</i> and <i>Neospora caninum</i> in rodents caught in Meshgin-Shahr District, Iran.<h4>Patients and methods</h4>In a cross-sectional study, brain samples were collected from 70 rodents caught in Meshgin-Shahr District during March and D ...[more]

PMID: 31908996

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Project description:BACKGROUND:Knowledge about parasitic infections is crucial information for animal health, particularly of free-ranging species that might come into contact with livestock and humans. METHODS:We investigated the seroprevalence of three tissue-cyst-forming apicomplexan parasites (Toxoplasma gondii, Neospora caninum and Besnoitia besnoiti) in 506 individuals of 12 wildlife species in Namibia using in-house enzyme linked immunosorbent assays (indirect ELISAs applying purified antigens) for screening and immunoblots as confirmatory tests. We included six species of the suborder Feliformia, four species of the suborder Caniformia and two species of the suborder Ruminantia. For the two species for which we had most samples and life-history information, i.e. cheetahs (Acinonyx jubatus, n = 250) and leopards (Panthera pardus, n = 58), we investigated T. gondii seroprevalence in relation to age class, sex, sociality (solitary, mother-offspring group, independent sibling group, coalition group) and site (natural habitat vs farmland). RESULTS:All but one carnivore species (bat-eared fox Otocyon megalotis, n = 4) were seropositive to T. gondii, with a seroprevalence ranging from 52.4% (131/250) in cheetahs to 93.2% (55/59) in African lions (Panthera leo). We also detected antibodies to T. gondii in 10.0% (2/20) of blue wildebeest (Connochaetes taurinus). Adult cheetahs and leopards were more likely to be seropositive to T. gondii than subadult conspecifics, whereas seroprevalence did not vary with sex, sociality and site. Furthermore, we measured antibodies to N. caninum in 15.4% (2/13) of brown hyenas (Hyaena brunnea) and 2.6% (1/39) of black-backed jackals (Canis mesomelas). Antibodies to B. besnoiti were detected in 3.4% (2/59) of African lions and 20.0% (4/20) of blue wildebeest. CONCLUSIONS:Our results demonstrate that Namibian wildlife species were exposed to apicomplexan parasites at different prevalences, depending on parasite and host species. In addition to serological work, molecular work is also needed to better understand the sylvatic cycle and the clear role of wildlife in the epidemiology of these parasites in southern Africa.

Dataset Information

Toxoplasma gondii And Neospora caninum In Brain Tissue Of Rodents In North-West Iran.

Publications

<i>Toxoplasma gondii</i> And <i>Neospora caninum</i> In Brain Tissue Of Rodents In North-West Iran.

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