Ontology highlight
ABSTRACT:
SUBMITTER: Lemos D
PROVIDER: S-EPMC6930183 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lemos Douglas D Oliveira Thaís T Martins Larissa L de Azevedo Vitória Ramos VR Rodrigues Mariana Figueiredo MF Ketzer Luisa Andrea LA Rumjanek Franklin David FD
Frontiers in oncology 20191218
Tumor cells exhibit rewired metabolism. We carried out comparative analyses attempting to investigate whether metabolic reprograming could be measured by isothermal microcalorimetry. Intact metastatic cell lines of tongue cell carcinoma, human and murine melanoma, lung, and breast tumors consistently released more heat than non-metastatic cells or cells displaying lower metastatic potential. In tongue squamous carcinoma cells mitochondrial enriched extract reproduced the heat release pattern of ...[more]