Ontology highlight
ABSTRACT:
SUBMITTER: Bruyneel AAN
PROVIDER: S-EPMC6932767 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Bruyneel Arne A N AAN Colas Alexandre R AR Karakikes Ioannis I Mercola Mark M
PloS one 20191226 12
Gene editing strategies, such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9), are revolutionizing biology. However, quantitative and sensitive detection of targeted mutations are required to evaluate and quantify the genome editing outcomes. Here we present AlleleProfileR, a new analysis tool, written in a combination of R and C++, with the ability to batch process the sequ ...[more]