Ontology highlight
ABSTRACT:
SUBMITTER: Qiu WX
PROVIDER: S-EPMC6933318 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Qiu Wu-Xia WX Ma Xiao-Li XL Lin Xiao X Zhao Fan F Li Di-Jie DJ Chen Zhi-Hao ZH Zhang Ke-Wen KW Zhang Ru R Wang Pai P Xiao Yun-Yun YY Miao Zhi-Ping ZP Dang Kai K Wu Xiao-Yang XY Qian Ai-Rong AR
Journal of cellular and molecular medicine 20191111 1
Microtubule actin cross-linking factor 1 (Macf1) is a spectraplakin family member known to regulate cytoskeletal dynamics, cell migration, neuronal growth and cell signal transduction. We previously demonstrated that knockdown of Macf1 inhibited the differentiation of MC3T3-E1 cell line. However, whether Macf1 could regulate bone formation in vivo is unclear. To study the function and mechanism of Macf1 in bone formation and osteogenic differentiation, we established osteoblast-specific Osterix ...[more]