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Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.


ABSTRACT: Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions that improve the experiences, outcomes, and health care of persons receiving hemodialysis. With the support of the Canadian Institutes of Health Research and its Strategy for Patient-Oriented Research, the Innovative Clinical Trials in Hemodialysis Centers initiative brought together Canadian and international kidney researchers, patients, health care providers, and health administrators to participate in a workshop held in Toronto, Canada, on June 2 and 3, 2018. The workshop served to increase knowledge and awareness about the conduct of innovative, pragmatic, cluster-randomized registry trials embedded into routine hemodialysis care and provided an opportunity to discuss and build support for new trial ideas. The workshop content included structured presentations, facilitated group discussions, and expert panel feedback. Partnerships and promising trial ideas borne out of the workshop will continue to be developed to support the implementation of future large-scale trials.

SUBMITTER: Lee EJ 

PROVIDER: S-EPMC6933546 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.

Lee Elliot J EJ   Patel Aakil A   Acedillo Rey R RR   Bachynski Jovina C JC   Barrett Ian I   Basile Erika E   Battistella Marisa M   Benjamin Derek D   Berry David D   Blake Peter G PG   Chan Patricia P   Bohm Clara J CJ   Clemens Kristin K KK   Cook Charles C   Dember Laura L   Dirk Jade S JS   Dixon Stephanie S   Fowler Elisabeth E   Getchell Leah L   Gholami Nazanine N   Goldstein Cory C   Hahn Emma E   Hogeterp Betty B   Huang Susan S   Hughes Michelle M   Jardine Meg J MJ   Kalatharan Shasikara S   Kilburn Shane S   Lacson Eduardo E   Leonard Sean S   Liberty Channing C   Lindsay Craig C   MacRae Jennifer M JM   Manns Braden J BJ   McCallum Janice J   McIntyre Christopher W CW   Molnar Amber O AO   Mustafa Reem A RA   Nesrallah Gihad E GE   Oliver Matthew J MJ   Pandes Michael M   Pandeya Sanjay S   Parmar Malvinder S MS   Rabin Elijah Z EZ   Riley Johnathan J   Silver Samuel A SA   Sontrop Jessica M JM   Sood Manish M MM   Suri Rita S RS   Tangri Navdeep N   Tascona Daniel J DJ   Thomas Alison A   Wald Ron R   Walsh Michael M   Weijer Charles C   Weir Matthew A MA   Vorster Hans H   Zimmerman Deborah D   Garg Amit X AX  

Canadian journal of kidney health and disease 20191226


Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions that improve the experiences, outcomes, and health care of persons receiving hemodialysis. With the support of the Canadian Institutes of Health Research and its Strategy for Patient-Oriented Research, the Innovative Clini  ...[more]

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