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Functionalized Magnetic Nanoparticles as Catalysts for Enantioselective Henry Reaction.

ABSTRACT: With the aim to easily recover and reuse the catalyst, an efficient amino alcohol catalyst previously tested in the asymmetric addition of diethylzinc to several aromatic aldehydes has been immobilized on proper functionalized superparamagnetic core-shell magnetite-silica nanoparticles and employed in the Henry reaction in the semi-homogeneous phase. The nanocatalyst exhibits a promising catalytic activity that remains unchanged in the three catalytic cycles performed. The results prove that highly efficient catalysts, by being immobilized on suitable magnetic nanosupports, can be easily recovered and reused, maintaining their catalytic behavior.

SUBMITTER: Sappino C

PROVIDER: S-EPMC6933584 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Functionalized Magnetic Nanoparticles as Catalysts for Enantioselective Henry Reaction.

Sappino Carla C Primitivo Ludovica L De Angelis Martina M Domenici Marzia Oneto MO Mastrodonato Andrea A Romdan Ilaria Ben IB Tatangelo Chiara C Suber Lorenza L Pilloni Luciano L Ricelli Alessandra A Righi Giuliana G

ACS omega 20191209 26

With the aim to easily recover and reuse the catalyst, an efficient amino alcohol catalyst previously tested in the asymmetric addition of diethylzinc to several aromatic aldehydes has been immobilized on proper functionalized superparamagnetic core-shell magnetite-silica nanoparticles and employed in the Henry reaction in the semi-homogeneous phase. The nanocatalyst exhibits a promising catalytic activity that remains unchanged in the three catalytic cycles performed. The results prove that hig ...[more]

PMID: 31891058

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