Current and Future Treatment Strategies for Rhabdomyosarcoma.
Ontology highlight
ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC6933601 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Current and Future Treatment Strategies for Rhabdomyosarcoma.
Chen Celine C Dorado Garcia Heathcliff H Scheer Monika M Henssen Anton G AG
Frontiers in oncology 20191220
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last four decades, there have been no significant improvements in clinical outcomes for advanced and metastatic RMS patients, underscoring a need for new treatment options for these groups. Despite significant advancements in our understanding of the genomic landscape and underlying biological mechanisms governing RMS that have ...[more]
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