Variation of growth characteristics of pneumococcus with environmental conditions.

ABSTRACT:

Background

Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood. We sought to determine the effect of environmental variability on growth in vitro and to assess variability between strains. We evaluated the effect of temperature and oxygen on the growth of 256 isolates representing 53 serotypes, recovered from healthy carriers and disease patients. Strains were grown at a range of temperatures, anaerobically or in ambient air with catalase, and were monitored by reading the optical density. Regression models evaluated variation in the characteristics of the growth curves.

Results

Most isolates grew to the maximal density at low temperatures (~33C) and under aerobic conditions. Ther

SUBMITTER: Tothpal A 

PROVIDER: S-EPMC6933730 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature