Ontology highlight
ABSTRACT:
SUBMITTER: Masoud AG
PROVIDER: S-EPMC6934203 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Masoud Andrew G AG Lin Jiaxin J Azad Abul K AK Farhan Maikel A MA Fischer Conrad C Zhu Lin F LF Zhang Hao H Sis Banu B Kassiri Zamaneh Z Moore Ronald B RB Kim Daniel D Anderson Colin C CC Vederas John C JC Adam Benjamin A BA Oudit Gavin Y GY Murray Allan G AG
The Journal of clinical investigation 20200101 1
Sustained, indolent immune injury of the vasculature of a heart transplant limits long-term graft and recipient survival. This injury is mitigated by a poorly characterized, maladaptive repair response. Vascular endothelial cells respond to proangiogenic cues in the embryo by differentiation to specialized phenotypes, associated with expression of apelin. In the adult, the role of developmental proangiogenic cues in repair of the established vasculature is largely unknown. We found that human an ...[more]