The changing landscape of clinical trials for mitochondrial diseases: 2011 to present.
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ABSTRACT:
SUBMITTER: Khayat D
PROVIDER: S-EPMC6934893 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
The changing landscape of clinical trials for mitochondrial diseases: 2011 to present.
Khayat Delia D Kurtz Tracie L TL Stacpoole Peter W PW
Mitochondrion 20191025
We reviewed the status of interventional clinical trials for primary mitochondrial diseases. Using national and international search engines, we found 48 randomized controlled trials (RCTs) registered as of May 15, 2019. Consilience between lay and professional mitochondrial disease communities to engage in RCTs has increased, as has progress in developing new disease and treatment biomarkers and potential therapies. The continued advancement of general knowledge of mitochondrial biology has fos ...[more]
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