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A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging.

ABSTRACT: Luminescent lanthanides provide a promising alternative to organic chromophores for cellular bioimaging and bioassay applications; efficacy is closely governed by their respective quantum yields. Conventionally utilized quantum-yield measurements for lanthanides are laborious and not amenable to rapid relative comparison of compound performance. Here, we introduce a high-throughput optical imaging method to determine and directly compare relative quantum yield using Cherenkov-radiation-mediated excitation of luminescent lanthanide complexes.

SUBMITTER: Cosby AG 

PROVIDER: S-EPMC6935265 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging.

Cosby Alexia G AG   Quevedo Gregory G   Boros Eszter E  

Inorganic chemistry 20190805 16

Luminescent lanthanides provide a promising alternative to organic chromophores for cellular bioimaging and bioassay applications; efficacy is closely governed by their respective quantum yields. Conventionally utilized quantum-yield measurements for lanthanides are laborious and not amenable to rapid relative comparison of compound performance. Here, we introduce a high-throughput optical imaging method to determine and directly compare relative quantum yield using Cherenkov-radiation-mediated  ...[more]

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