Ontology highlight
ABSTRACT:
SUBMITTER: Gregor C
PROVIDER: S-EPMC6936394 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Gregor Carola C Pape Jasmin K JK Gwosch Klaus C KC Gilat Tanja T Sahl Steffen J SJ Hell Stefan W SW
Proceedings of the National Academy of Sciences of the United States of America 20191202 52
Bioluminescence-based imaging of living cells has become an important tool in biological and medical research. However, many bioluminescence imaging applications are limited by the requirement of an externally provided luciferin substrate and the low bioluminescence signal which restricts the sensitivity and spatiotemporal resolution. The bacterial bioluminescence system is fully genetically encodable and hence produces autonomous bioluminescence without an external luciferin, but its brightness ...[more]