Proximal femoral head transcriptome reveals novel candidate genes related to epiphysiolysis in broiler chickens.
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ABSTRACT:
SUBMITTER: de Oliveira Peixoto J
PROVIDER: S-EPMC6937697 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
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Proximal femoral head transcriptome reveals novel candidate genes related to epiphysiolysis in broiler chickens.
de Oliveira Peixoto Jane J Savoldi Igor Ricardo IR Ibelli Adriana Mércia Guaratini AMG Cantão Maurício Egídio ME Jaenisch Fátima Regina Ferreira FRF Giachetto Poliana Fernanda PF Settles Matthew Lee ML Zanella Ricardo R Marchesi Jorge Augusto Petroli JAP Pandolfi José Rodrigo JR Coutinho Luiz Lehmann LL Ledur Mônica Corrêa MC
BMC genomics 20191230 1
<h4>Background</h4>The proximal femoral head separation (FHS) or epiphysiolysis is a prevalent disorder affecting the chicken femur epiphysis, being considered a risk factor to infection which can cause bacterial chondronecrosis with osteomyelitis in broilers. To identify the genetic mechanisms involved in epiphysiolysis, differentially expressed (DE) genes in the femur of normal and FHS-affected broilers were identified using RNA-Seq technology. Femoral growth plate (GP) samples from 35-day-old ...[more]
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