Longitudinal Phenotypes Improve Genotype Association for Hyperketonemia in Dairy Cattle.
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ABSTRACT:
SUBMITTER: Yepes FAL
PROVIDER: S-EPMC6941043 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Longitudinal Phenotypes Improve Genotype Association for Hyperketonemia in Dairy Cattle.
Yepes Francisco A Leal FAL Nydam Daryl V DV Mann Sabine S Caixeta Luciano L McArt Jessica A A JAA Overton Thomas R TR Wakshlag Joseph J JJ Huson Heather J HJ
Animals : an open access journal from MDPI 20191201 12
The objective of our study was to identify genomic regions associated with varying concentrations of non-esterified fatty acid (NEFA), β-hydroxybutyrate (BHB), and the development of hyperketonemia (HYK) in longitudinally sampled Holstein dairy cows. Our study population consisted of 147 multiparous cows intensively characterized by serial NEFA and BHB concentrations. To identify individuals with contrasting combinations in longitudinal BHB and NEFA concentrations, phenotypes were established us ...[more]
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