Ontology highlight
ABSTRACT:
SUBMITTER: Serin Harmanci A
PROVIDER: S-EPMC6941987 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Serin Harmanci Akdes A Harmanci Arif O AO Zhou Xiaobo X
Nature communications 20200103 1
RNA sequencing experiments generate large amounts of information about expression levels of genes. Although they are mainly used for quantifying expression levels, they contain much more biologically important information such as copy number variants (CNVs). Here, we present CaSpER, a signal processing approach for identification, visualization, and integrative analysis of focal and large-scale CNV events in multiscale resolution using either bulk or single-cell RNA sequencing data. CaSpER integ ...[more]