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Summary of the Third Annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.


ABSTRACT: The third annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on November 29, 2018, at the American Society of Hematology (ASH) annual meeting. This workshop featured the latest research focused on minimal residual disease (MRD) assessment and immune profiling (IP) in myeloma as well as discussion of the statistical and regulatory issues intrinsic to the development of MRD as a surrogate endpoint. In this report, we provide a summary of the workshop and focus on the integration of MRD and IP assessment into trial design and clinical practice.

SUBMITTER: Holstein SA 

PROVIDER: S-EPMC6942175 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Summary of the Third Annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

Holstein Sarah A SA   Al-Kadhimi Zaid Z   Costa Luciano J LJ   Hahn Theresa T   Hari Parameswaran P   Hillengass Jens J   Jacob Allison A   Munshi Nikhil C NC   Oliva Stefania S   Pasquini Marcelo C MC   Shi Qian Q   Stadtmauer Edward A EA   Waldvogel Stephanie L SL   McCarthy Philip L PL  

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20190914 1


The third annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on November 29, 2018, at the American Society of Hematology (ASH) annual meeting. This workshop featured the latest research focused on minimal residual disease (MRD) assessment and immune profiling (IP) in myeloma as well as discussion of the statistical and regulatory issues intrinsic to the development of MRD as a surrogate endpoi  ...[more]

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