Ontology highlight
ABSTRACT:
SUBMITTER: Yu F
PROVIDER: S-EPMC6943076 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Yu Fulong F Li Kai K Li Shuangquan S Liu Jiaqi J Zhang Yan Y Zhou Meng M Zhao Hengqiang H Chen Hongyan H Wu Nan N Liu Zhihua Z Su Jianzhong J
Nucleic acids research 20200101 D1
Epigenetic alterations, including 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) and nucleosome positioning (NP), in cell-free DNA (cfDNA) have been widely observed in human diseases, and many available cfDNA-based epigenome-wide profiles exhibit high sensitivity and specificity in disease detection and classification. However, due to the lack of efficient collection, standardized quality control, and analysis procedures, efficiently integrating and reusing these data remain considerable ...[more]