Ontology highlight
ABSTRACT:
SUBMITTER: Fan X
PROVIDER: S-EPMC6943692 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Fan Xia X Chen Rongshun R Han Jie J He Zhengjie Z
Molecules (Basel, Switzerland) 20191216 24
Tri- or tetrasubstituted furans have been prepared from terminal activated olefins and acyl chlorides or anhydrides by a multicomponental convergent synthesis mode. Instead of stoichiometric <i>n</i>Bu<sub>3</sub>P, only catalytic <i>n</i>Bu<sub>3</sub>P or <i>n</i>Bu<sub>3</sub>P=O is needed to furnish the furans in modest to excellent yields with a good functional group tolerance under the aid of reducing agent silane. This synthetic method features a silane-driven catalytic intramolecular Wit ...[more]