Ontology highlight
ABSTRACT:
SUBMITTER: Hjornevik T
PROVIDER: S-EPMC6944163 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Hjørnevik Trine T Cipriano Peter W PW Shen Bin B Park Jun Hyung JH Gulaka Praveen P Holley Dawn D Gandhi Harsh H Yoon Daehyun D Mittra Erik S ES Zaharchuk Greg G Gambhir Sanjiv S SS McCurdy Christopher R CR Chin Frederick T FT Biswal Sandip S
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20170601 12
The purpose of this study was to assess safety, biodistribution, and radiation dosimetry in humans for the highly selective σ-1 receptor PET agent <sup>18</sup>F-6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo[<i>d</i>]thiazol-2(3H)-one (<sup>18</sup>F-FTC-146). <b>Methods:</b> Ten healthy volunteers (5 women, 5 men; age ± SD, 34.3 ± 6.5 y) were recruited, and written informed consent was obtained from all participants. Series of whole-body PET/MRI examinations were acquired for up to 3 h after ...[more]