On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data.
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ABSTRACT:
SUBMITTER: Witulla B
PROVIDER: S-EPMC6944332 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data.
Witulla Barbara B Goerig Nicole N Putz Florian F Frey Benjamin B Engelhorn Tobias T Dörfler Arnd A Uder Michael M Fietkau Rainer R Bert Christoph C Laun Frederik Bernd FB
PloS one 20200106 1
Radiotherapy (RT) is commonly applied for the treatment of glioblastoma multiforme (GBM). Following the planning target volume (PTV) definition procedure standardized in guidelines, a 20% risk of missing non-local recurrences is present. Purpose of this study was to evaluate whether diffusion tensor imaging (DTI)-based fiber tracking may be beneficial for PTV definition taking into account the prediction of distant recurrences. 56 GBM patients were examined with magnetic resonance imaging (MRI) ...[more]
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