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Management of chronic myeloid leukemia in children and adolescents: Recommendations from the Children's Oncology Group CML Working Group.


ABSTRACT: Chronic myeloid leukemia (CML) accounts for 2-3% of leukemias in children under 15 and 9% in adolescents aged 15-19. The diagnosis and management of CML in children, adolescents, and young adults have several differences compared to that in adults. This review outlines the diagnosis and management of the underlying disease as well as challenges that can occur when dealing with CML in this patient population.

SUBMITTER: Athale U 

PROVIDER: S-EPMC6944522 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Management of chronic myeloid leukemia in children and adolescents: Recommendations from the Children's Oncology Group CML Working Group.

Athale Uma U   Hijiya Nobuko N   Patterson Briana C BC   Bergsagel John J   Andolina Jeffrey R JR   Bittencourt Henrique H   Schultz Kirk R KR   Burke Michael J MJ   Redell Michele S MS   Kolb E Anders EA   Johnston Donna L DL  

Pediatric blood & cancer 20190610 9


Chronic myeloid leukemia (CML) accounts for 2-3% of leukemias in children under 15 and 9% in adolescents aged 15-19. The diagnosis and management of CML in children, adolescents, and young adults have several differences compared to that in adults. This review outlines the diagnosis and management of the underlying disease as well as challenges that can occur when dealing with CML in this patient population. ...[more]

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