Ontology highlight
ABSTRACT:
SUBMITTER: Hill LK
PROVIDER: S-EPMC6945506 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Hill Lindsay K LK Frezzo Joseph A JA Katyal Priya P Hoang Dung Minh DM Ben Youss Gironda Zakia Z Xu Cynthia C Xie Xuan X Delgado-Fukushima Erika E Wadghiri Youssef Z YZ Montclare Jin Kim JK
ACS nano 20190219 3
Engineered proteins provide an interesting template for designing fluorine-19 (<sup>19</sup>F) magnetic resonance imaging (MRI) contrast agents, yet progress has been hindered by the unpredictable relaxation properties of fluorine. Herein, we present the biosynthesis of a protein block copolymer, termed "fluorinated thermoresponsive assembled protein" (F-TRAP), which assembles into a monodisperse nanoscale micelle with interesting <sup>19</sup>F NMR properties and the ability to encapsulate and ...[more]