Ontology highlight
ABSTRACT:
SUBMITTER: Fuchigami A
PROVIDER: S-EPMC6945792 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Fuchigami Ayako A Shigiyama Fumika F Kitazawa Toru T Okada Yosuke Y Ichijo Takamasa T Higa Mariko M Hiyoshi Toru T Inoue Ikuo I Iso Kaoru K Yoshii Hidenori H Hirose Takahisa T Kumashiro Naoki N
Cardiovascular diabetology 20200107 1
<h4>Background</h4>Few prospective studies have compared the cardiovascular benefits of sodium-glucose cotransporter-2 (SGLT2) inhibitors and dipeptidyl peptidase 4 (DPP-4) inhibitors. We aimed to clarify the efficacy of dapagliflozin versus sitagliptin for modulating cardiometabolic risk factors including high glycated hemoglobin (HbA1c) levels, hypoglycemia, and body weight.<h4>Methods</h4>This prospective, randomized, open-label, blinded-endpoint, parallel-group trial enrolled 340 Japanese pa ...[more]