CDKN2A testing and genetic counseling promote reductions in objectively measured sun exposure one year later.
Ontology highlight
ABSTRACT:
SUBMITTER: Stump TK
PROVIDER: S-EPMC6946876 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
CDKN2A testing and genetic counseling promote reductions in objectively measured sun exposure one year later.
Stump Tammy K TK Aspinwall Lisa G LG Drummond Danielle M DM Taber Jennifer M JM Kohlmann Wendy W Champine Marjan M Cassidy Pamela B PB Petrie Tracy T Liley Ben B Leachman Sancy A SA
Genetics in medicine : official journal of the American College of Medical Genetics 20190802 1
<h4>Purpose</h4>This study investigated whether genetic counseling and test reporting for the highly penetrant CDKN2A melanoma predisposition gene promoted decreases in sun exposure.<h4>Methods</h4>A prospective, nonequivalent control group design compared unaffected participants (N = 128, M<sub>age</sub> = 35.24, 52% men) from (1) families known to carry a CDKN2A pathogenic variant, who received counseling about management recommendations and a positive or negative genetic test result and (2) n ...[more]
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