Metabolic Syndrome Including Glycated Hemoglobin A1c in Adults: Is It Time to Change?

ABSTRACT: (1) Background: To assess the suitability of replacing conventional markers used for insulin resistance and dysglycemia by HbA1c in both the quantitative and qualitative metabolic syndrome (MetS) definition criteria; (2) Methods: Confirmatory factorial analysis was used to compare three quantitative definitions of MetS that consisted of many single-factor models, one of which included HbA1c as the dysglycemia indicator. After that, the model with the better goodness-of-fit was selected. Furthermore, a new MetS qualitative definition was proposed by replacing fasting plasma glucose with HbA1c > 5.7% in the International Diabetes Federation (IDF) definition. The clinical performance of these two MetS criteria (IDF and IDF-modified including HbA1c as the dysglycemia indicator) to predict vasc

SUBMITTER: Cavero-Redondo I 

PROVIDER: S-EPMC6947260 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature