Ontology highlight
ABSTRACT:
SUBMITTER: Rapado-Gonzalez O
PROVIDER: S-EPMC6947363 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Rapado-González Óscar Ó Majem Blanca B Álvarez-Castro Ana A Díaz-Peña Roberto R Abalo Alicia A Suárez-Cabrera Leticia L Gil-Moreno Antonio A Santamaría Anna A López-López Rafael R Muinelo-Romay Laura L Suarez-Cunqueiro María Mercedes MM
Journal of clinical medicine 20191120 12
Salivary microRNAs (miRNAs) are of high interest as diagnostic biomarkers for non-oral cancer. However, little is known about their value for colorectal cancer (CRC) detection. Our study aims to characterize salivary miRNAs in order to identify non-invasive markers for CRC diagnosis. The screening of 754 miRNAs was performed in saliva samples from 14 CRC and 10 healthy controls. The differential expressed miRNAs were validated by RT-qPCR in 51 CRC, 19 adenomas and 37 healthy controls. Receiver o ...[more]