Ontology highlight
ABSTRACT:
SUBMITTER: Cheng G
PROVIDER: S-EPMC6948008 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Cheng Gang G Pan Jing J Podsiadly Radoslaw R Zielonka Jacek J Garces Alexander M AM Dias Duarte Machado Luiz Gabriel LG Bennett Brian B McAllister Donna D Dwinell Michael B MB You Ming M Kalyanaraman Balaraman B
Free radical biology & medicine 20191223
Previous studies have shown that reactive oxygen species (ROS) such as superoxide or hydrogen peroxide generated at low levels can exert a tumor-promoting role via a redox-signaling mechanism. Reports also suggest that both tumorigenesis and tumor growth are associated with enhanced ROS formation. However, whether ROS levels or ROS-derived oxidative marker levels increase during tumor growth remains unknown. In this study, in vivo bioluminescence imaging with a boronate-based pro-luciferin probe ...[more]