Ontology highlight
ABSTRACT:
SUBMITTER: Liang L
PROVIDER: S-EPMC6948297 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Liang Li L Li Feng-Jiao FJ Liu Xin X Mu Jian-Kang JK Wang Xi X Dong Jin-Cai JC Zeng Lin-Xi LX Gu Wen W Li Jing-Ping JP Yang Xing-Xin XX Yu Jie J
BioMed research international 20191216
In recent years, the incidence of diseases associated with hepatic injury has increased in prevalence. Targeting the mitochondria to protect liver function has gained momentum due to their central role in energy production, apoptotic cell death, oxidative stress, calcium homeostasis, and lipid metabolism. In this study, we employed a hepatic mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method (CM-HMC) to identify hepatic mitochondria ligands from medicin ...[more]