Epstein-Barr Virus BALF0 and BALF1 Modulate Autophagy.
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ABSTRACT:
SUBMITTER: Shao Z
PROVIDER: S-EPMC6950364 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Epstein-Barr Virus BALF0 and BALF1 Modulate Autophagy.
Shao Zhouwulin Z Borde Chloé C Quignon Frédérique F Escargueil Alexandre A Maréchal Vincent V
Viruses 20191127 12
Autophagy is an essential catabolic process that degrades cytoplasmic components within the lysosome, therefore ensuring cell survival and homeostasis. A growing number of viruses, including members of the Herpesviridae family, have been shown to manipulate autophagy to facilitate their persistence or optimize their replication. Previous works showed that the Epstein-Barr virus (EBV), a human transforming gammaherpesvirus, hijacked autophagy during the lytic phase of its cycle, possibly to favor ...[more]
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