Ontology highlight
ABSTRACT:
SUBMITTER: Koirala B
PROVIDER: S-EPMC6952583 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Koirala Bimal B Tal-Gan Yftah Y
Chembiochem : a European journal of chemical biology 20191015 3
The rapid increase in multidrug-resistant pathogens is a major health concern that could bring mankind back to the pre-antibiotic era. Streptococcus pneumoniae is a highly recombinogenic opportunistic pathogen that causes a variety of deadly diseases and rapidly develops resistance to current antibiotic treatments. S. pneumoniae pathogenicity is dependent on a cell-density communication mechanism, or quorum sensing (QS), termed the competence regulon. In this work, we set out to design signal-ba ...[more]