Ontology highlight
ABSTRACT:
SUBMITTER: Yakymiv Y
PROVIDER: S-EPMC6952987 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Yakymiv Yuliya Y Augeri Stefania S Fissolo Giulia G Peola Silvia S Bracci Cristiano C Binaschi Monica M Bellarosa Daniela D Pellacani Andrea A Ferrero Enza E Ortolan Erika E Funaro Ada A
Cells 20191205 12
<b>:</b> Human CD157/BST-1 and CD38 are dual receptor-enzymes derived by gene duplication that belong to the ADP ribosyl cyclase gene family. First identified over 30 years ago as Mo5 myeloid differentiation antigen and 10 years later as Bone Marrow Stromal Cell Antigen 1 (BST-1), CD157 proved not to be restricted to the myeloid compartment and to have a diversified functional repertoire ranging from immunity to cancer and metabolism. Despite being a NAD<sup>+</sup>-metabolizing ectoenzyme ancho ...[more]