PI3K/AKT/mTOR inhibitors for advanced or recurrent endometrial cancer.
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ABSTRACT:
SUBMITTER: Roncolato F
PROVIDER: S-EPMC6953296 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
PI3K/AKT/mTOR inhibitors for advanced or recurrent endometrial cancer.
Roncolato Felicia F Lindemann Kristina K Willson Melina L ML Martyn Julie J Mileshkin Linda L
The Cochrane database of systematic reviews 20191007
<h4>Background</h4>Endometrial cancer is one of the most common gynaecological cancers in developed countries. Treatment of advanced endometrial cancer usually involves radiotherapy, chemotherapy, endocrine therapy or a combination of these. However, survival outcomes are poor in advanced or metastatic disease. Better systemic treatment options are needed to improve survival and safety outcomes for these women. The PI3K/AKT/mTOR pathway is a frequently altered signalling pathway in endometrial c ...[more]
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