Ontology highlight
ABSTRACT:
SUBMITTER: Moreno-Morcillo M
PROVIDER: S-EPMC6954437 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Moreno-Morcillo María M Francisco-Velilla Rosario R Embarc-Buh Azman A Fernández-Chamorro Javier J Ramón-Maiques Santiago S Martinez-Salas Encarnacion E
Nucleic acids research 20200101 2
In all organisms, a selected type of proteins accomplishes critical roles in cellular processes that govern gene expression. The multifunctional protein Gemin5 cooperates in translation control and ribosome binding, besides acting as the RNA-binding protein of the survival of motor neuron (SMN) complex. While these functions reside on distinct domains located at each end of the protein, the structure and function of the middle region remained unknown. Here, we solved the crystal structure of an ...[more]