Ontology highlight
ABSTRACT:
SUBMITTER: Landry ML
PROVIDER: S-EPMC6956358 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
ACS medicinal chemistry letters 20191211 1
The importance of physicochemical property calculation and measurement is well-established in drug discovery. In particular, lipophilicity predictions play a central role in target design and prioritization. While significant progress has been made in our ability to calculate both log<i>P</i> and log<i>D</i>, the quality of these predictions is limited by the size and diversity of the underlying data set. Access to diverse data sets and advanced models is often limited to large organizations or ...[more]