Ontology highlight
ABSTRACT:
SUBMITTER: Kaddouri Y
PROVIDER: S-EPMC6956760 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Heliyon 20200109 1
Novel heterocyclic compounds containing pyrazole, thiazole and pyridine moieties were designed and prepared based on the condensation reaction between 1,3-thiazole or aminopyridine derivatives and 1H-pyrazole,3,5-dimethyl-1H-pyrazole or 1,2,4-triazole. Their structures were confirmed with FTIR, <sup>1</sup>H and <sup>13</sup>C NMR analyses. DPPH scavenging assay was used to evaluate their antioxidant potential. The ligand <b>4</b> showed the best antioxidant activity with an IC<sub>50</sub> = 4. ...[more]