Ontology highlight
ABSTRACT:
SUBMITTER: Francisco-Garcia AS
PROVIDER: S-EPMC6958500 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Francisco-Garcia Ana S AS Garrido-Martín Eva M EM Rupani Hitasha H Lau Laurie C K LCK Martinez-Nunez Rocio T RT Howarth Peter H PH Sanchez-Elsner Tilman T
Non-coding RNA 20191102 4
MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such as exosomes. In this study, we particularly focused on microRNA cargo of nanovesicles in bronchoalveolar lavage of severe asthmatic patients. We extracted nanovesicle RNA using a serial filtration method. RNA content was analyzed with small RNA sequencing and mapped to pathways affected using WebGes ...[more]