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Racial disparities in chemotherapy administration for early-stage breast cancer: a systematic review and meta-analysis.


ABSTRACT: PURPOSE:We conducted a systematic review and meta-analysis to measure the extent to which race is associated with delayed initiation or receipt of inadequate chemotherapy among women with early-stage breast cancer. METHODS:We performed a systematic search of all articles published from January 1987 until June 2017 within four databases: PubMed/Medline, EMBASE, CINAHL, and Cochrane CENTRAL. Eligible studies were US-based and examined the influence of race on chemotherapy delays, cessation, or dose reductions among women with stage I, II, or III breast cancer. Data were pooled using a random effects model. RESULTS:A total of twelve studies were included in the quantitative analysis. Blacks were significantly more likely than whites to have delays to initiation of adjuvant therapy of 90 days or more (OR 1.41, 95% CI 1.06-1.87; X² = 31.05, p?

SUBMITTER: Green AK 

PROVIDER: S-EPMC6958704 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Racial disparities in chemotherapy administration for early-stage breast cancer: a systematic review and meta-analysis.

Green Angela K AK   Aviki Emeline M EM   Matsoukas Konstantina K   Patil Sujata S   Korenstein Deborah D   Blinder Victoria V  

Breast cancer research and treatment 20180809 2


<h4>Purpose</h4>We conducted a systematic review and meta-analysis to measure the extent to which race is associated with delayed initiation or receipt of inadequate chemotherapy among women with early-stage breast cancer.<h4>Methods</h4>We performed a systematic search of all articles published from January 1987 until June 2017 within four databases: PubMed/Medline, EMBASE, CINAHL, and Cochrane CENTRAL. Eligible studies were US-based and examined the influence of race on chemotherapy delays, ce  ...[more]

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