TranCEP: Predicting the substrate class of transmembrane transport proteins using compositional, evolutionary, and positional information.
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ABSTRACT:
SUBMITTER: Alballa M
PROVIDER: S-EPMC6959595 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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TranCEP: Predicting the substrate class of transmembrane transport proteins using compositional, evolutionary, and positional information.
Alballa Munira M Aplop Faizah F Butler Gregory G
PloS one 20200114 1
Transporters mediate the movement of compounds across the membranes that separate the cell from its environment and across the inner membranes surrounding cellular compartments. It is estimated that one third of a proteome consists of membrane proteins, and many of these are transport proteins. Given the increase in the number of genomes being sequenced, there is a need for computational tools that predict the substrates that are transported by the transmembrane transport proteins. In this paper ...[more]
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