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Association between changes in QRS width and echocardiographic responses to cardiac resynchronization therapy: A systematic review and meta-analysis.

ABSTRACT: BACKGROUND:Numerous studies have illustrated the association of QRS width with the incidence of echocardiographic response to cardiac resynchronization therapy (CRT). This study aimed to summarize the observational studies regarding the magnitude of change in QRS width between responders and nonresponders to CRT. METHODS:The PubMed, Embase, and the Cochrane Library were systematically searched for relevant studies investigating the changes of QRS width with the incidence of echocardiographic response to CRT from inception till May 2019. The pooled weighted mean difference (WMD) with 95% confidence interval (CI) was calculated through random-effects model. RESULTS:Five prospective and 6 retrospective studies with a total of 1524 patients were selected for final analysis. The reduction of QRS width in responders was significantly greater than nonresponders (WMD: -20.54 ms; 95% CI: -26.78 to -14.29; P?

SUBMITTER: Ma J 

PROVIDER: S-EPMC6959877 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Association between changes in QRS width and echocardiographic responses to cardiac resynchronization therapy: A systematic review and meta-analysis.

Ma Jing J   Liu Yi Y   Dong Yun Y   Chen Ming M   Xia Lianghua L   Xu Min M  

Medicine 20200101 2

<h4>Background</h4>Numerous studies have illustrated the association of QRS width with the incidence of echocardiographic response to cardiac resynchronization therapy (CRT). This study aimed to summarize the observational studies regarding the magnitude of change in QRS width between responders and nonresponders to CRT.<h4>Methods</h4>The PubMed, Embase, and the Cochrane Library were systematically searched for relevant studies investigating the changes of QRS width with the incidence of echoca  ...[more]

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