Ontology highlight
ABSTRACT:
SUBMITTER: Nam KI
PROVIDER: S-EPMC6962250 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Frontiers in molecular neuroscience 20200109
The pineal gland maintains the circadian rhythm in the body by secreting the hormone melatonin. Alzheimer's disease (AD) is the most common neurodegenerative disease. Pineal gland impairment in AD is widely observed, but no study to date has analyzed the transcriptome in the pineal glands of AD. To establish resources for the study on pineal gland dysfunction in AD, we performed a transcriptome analysis of the pineal glands of AD model mice and compared them to those of wild type mice. We identi ...[more]