Ontology highlight
ABSTRACT:
SUBMITTER: Vieira D
PROVIDER: S-EPMC6963225 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Vieira Daniela D Durães João J Baldeiras Inês I Santiago Beatriz B Duro Diana D Lima Marisa M Leitão Maria João MJ Tábuas-Pereira Miguel M Santana Isabel I
Diagnostics (Basel, Switzerland) 20191025 4
Frontotemporal lobar degeneration, the neuropathological substrate of frontotemporal dementia (FTD), is characterized by the deposition of protein aggregates, including tau. Evidence has shown concomitant amyloid pathology in some of these patients, which seems to contribute to a more aggressive disease. Our aim was to evaluate cerebrospinal fluid (CSF) amyloid-beta as a predictor of the mortality of FTD patients. We included 99 patients diagnosed with FTD-both behavioral and language variants-w ...[more]